To "upend" means to completely disrupt, overturn, or drastically change the established order or structure of something. It implies a significant shift or alteration that can potentially have far-reaching consequences. When something is upended, it is turned upside down or transformed in a way that challenges conventional norms or expectations. The term often carries a sense of innovation, transformation, and sometimes even a hint of upheaval, indicating that the changes are not just minor adjustments but rather a fundamental reimagining of the status quo.